Isisombululo esipheleleyo seeNkampani ze-IVD zokusika iiNdleko zeMpahla eziPhakamileyo

DMT-dC(Bz)-CE Phosphoramidite (umgangatho) DMT-dG(i-Bu)-CE Phosphoramidite (umgangatho) I-DMT-dG(dmf)-CE Phosphoramidite (i-cleavage ekhawulezayo) I-DMT-dT-CE Phosphoramidite DMT-dA(Bz)-CE Phosphoramidite

 

Ehlabathini lonke kufuneka lijongane neendleko eziphezulu zezinto eziphathekayo, kwaye zichaphazela kakhulu i-IVD kunye nezinye iinkampani ezikolu shishino.

Ukunceda bonke abathengi kule meko, i-HonyaBiotech inesisombululo esipheleleyo se-Oligo synthesis cycle yemveliso ye-IVD feedstock.-HY-12 phakathi kwe-Synthesizer, ukuxhasa i-instrumentation ezenzekelayo ngokupheleleyo, umgangatho ophezulu we-SynthesisAmiditekunye ne-SynthesisIireagentskunye neenkonzo zoqeqesho ezipheleleyo zemveliso.

Kwiinyanga ze-3, abanye abathengi bethu be-feeback bayakwazi ukugqiba ukuveliswa kwayo kwe-IVD feedstock, ukunciphisa kakhulu iindleko zokuvelisa, ngelixa befumana isikhokelo senkqubo epheleleyo kunye nokuphendula kwimiba yenkqubo yokuvelisa nangaliphi na ixesha, ukugcina ixesha kunye neendleko.

 

未命名的设计(1)

 

 

Unyino lwe-oligonucleotide synthesis yesigaba esiqinileyo

Nangona udityaniso lwe-DNA lusebenza ngokufanelekileyo, ukungcola ngokuqinisekileyo kuyafumba.I-synthesis ye-oligodeoxynucleotide ye-20mer ibandakanya amanyathelo ekhemikhali angaphezu kwe-100, ngalinye linamandla okuphendula okungafunekiyo.Ukongezelela ekuqokeleleni iziqwenga ezingaphumeleliyo ezibangelwa ukudibanisa okungaphelelanga, ukukhutshwa kwekhonkco ye-oligonucleotide emva kokutshatyalaliswa kunokuvelisa iziqwenga ezinqamlekileyo.

Ukuguqulwa kweekhemikhali zesiseko se-heterocycles ngamanye amaxesha kwenzeka, kwaye iimveliso ze-oligonucleotide ezilungisiweyo zinokuba zii-mutagens, ezinokubangela iingxaki ezinzulu kwiimvavanyo zebhayoloji.Ngenxa yokwenzeka kweempendulo zecala, ukufumana i-oligonucleotides ecocekileyo kakhulu, kuyimfuneko ukusebenzisa eyona ndlela yokucoca.


Ixesha lokuposa: Sep-06-2022